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truB protein (Klebsiella pneumoniae) - STRING interaction network
"truB" - tRNA pseudouridine synthase B in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (314 aa)    
Predicted Functional Partners:
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA (133 aa)
 
   
  0.984
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (896 aa)
 
  0.965
ksgA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (273 aa)
 
 
  0.908
JG24_23345
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA (431 aa)
 
 
  0.895
rpsA
SSU ribosomal protein S1p; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method- Protein Homology (557 aa)
   
 
  0.877
yebU
Ribosomal RNA small subunit methyltransferase F ## SSU rRNA m5C1407; In Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; Derived by automated computational analysis using gene prediction method- Protein Homology (477 aa)
 
 
  0.844
guaA
GMP synthase (glutamine-hydrolyzing); Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (525 aa)
   
   
  0.844
JG24_18565
Cetylates the wobble base C34 of the elongation-specific methionine tRNA; Derived by automated computational analysis using gene prediction method- Protein Homology (667 aa)
     
 
  0.842
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
   
   
  0.834
JG24_29510
Riboflavin biosynthesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ribF family (312 aa)
 
   
  0.834
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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