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lptC protein (Klebsiella pneumoniae) - STRING interaction network
"lptC" - Lipopolysaccharide export system protein LptC in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lptCLipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA; Belongs to the LptC family (191 aa)    
Predicted Functional Partners:
lptA
Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm (181 aa)
 
  0.996
JG24_22940
Lipopolysaccharide ABC transporter, ATP-binding protein LptB; Derived by automated computational analysis using gene prediction method- Protein Homology (241 aa)
 
 
  0.973
JG24_22925
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC; Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family (188 aa)
 
   
  0.961
lptE
LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane (196 aa)
   
     
  0.897
JG24_22920
Arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method- Protein Homology (328 aa)
 
   
  0.897
JG24_22915
Inner membrane protein YrbG, predicted calcium/sodium-proton antiporter; YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; Derived by automated computational analysis using gene prediction method- Protein Homology (325 aa)
   
 
  0.875
JG24_22890
Derived by automated computational analysis using gene prediction method- Protein Homology (96 aa)
 
        0.864
lptD
LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane (782 aa)
 
 
  0.857
JG24_22950
YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; Derived by automated computational analysis using gene prediction method- Protein Homology (95 aa)
 
   
  0.839
JG24_22895
Uncharacterized ABC transporter, auxiliary component YrbC; Involved in maintaining outer membrane lipid asymmetry; Derived by automated computational analysis using gene prediction method- Protein Homology (211 aa)
 
        0.833
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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