STRINGSTRING
aaeX protein (Klebsiella pneumoniae) - STRING interaction network
"aaeX" - Membrane protein AaeX in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aaeXMembrane protein AaeX; the gene is a member of the aaeXAB operon; Derived by automated computational analysis using gene prediction method- Protein Homology (67 aa)    
Predicted Functional Partners:
aaeB
P-hydroxybenzoic acid efflux pump subunit AaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (655 aa)
 
        0.973
aaeA
P-hydroxybenzoic acid efflux pump subunit AaeA; Forms an efflux pump with AaeB (310 aa)
        0.961
mzrA
Modulator protein MzrA; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (127 aa)
   
          0.726
JG24_20105
Putative cytochrome oxidase subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (108 aa)
   
          0.711
JG24_27980
Putative exported protein; In Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; Derived by automated computational analysis using gene prediction method- Protein Homology (102 aa)
   
          0.710
JG24_23155
Putative transcriptional regulator LYSR-type; For aaeXAB operon; Derived by automated computational analysis using gene prediction method- Protein Homology (309 aa)
 
          0.698
ompX
Outer membrane protein X; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method- Protein Homology (171 aa)
   
          0.694
JG24_23120
Probable exported protein YPO3518; Derived by automated computational analysis using gene prediction method- Protein Homology (87 aa)
   
        0.685
JG24_24115
DcrB protein; Derived by automated computational analysis using gene prediction method- Protein Homology (185 aa)
   
          0.679
JG24_15775
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (96 aa)
   
          0.676
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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