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JG24_23225 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_23225" - An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism in Klebsiella pneumoniae
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second shell of interactors
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JG24_23225An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method- Protein Homology (449 aa)    
Predicted Functional Partners:
JG24_23220
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (155 aa)
  0.999
JG24_23075
Catalyzes the formation of pyruvate from oxaloacetate; Derived by automated computational analysis using gene prediction method- Protein Homology (589 aa)
 
 
  0.998
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA; Belongs to the AccD/PCCB family (306 aa)
 
  0.989
JG24_03095
Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; Derived by automated computational analysis using gene prediction method- Protein Homology (319 aa)
 
  0.981
JG24_08175
Malonyl CoA-acyl carrier protein transacylase; Derived by automated computational analysis using gene prediction method- Protein Homology (309 aa)
 
  0.981
JG24_08170
FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; Derived by automated computational analysis using gene prediction method- Protein Homology (317 aa)
 
 
  0.971
JG24_10255
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (1175 aa)
       
  0.963
JG24_27415
Acetyl-coenzyme A synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method- Protein Homology (652 aa)
   
  0.936
JG24_03495
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method- Protein Homology (511 aa)
   
   
  0.925
JG24_17900
Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method- Protein Homology (715 aa)
     
 
  0.921
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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