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fis protein (Klebsiella pneumoniae) - STRING interaction network
"fis" - DNA-binding protein Fis in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fisDNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (98 aa)    
Predicted Functional Partners:
dusB
tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family (321 aa)
   
  0.994
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (329 aa)
   
 
  0.690
csrA
Carbon storage regulator homolog; Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (61 aa)
   
     
  0.677
rpsT
SSU ribosomal protein S20p; Binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; Derived by automated computational analysis using gene prediction method- Protein Homology (87 aa)
 
        0.616
JG24_25840
GTP-binding protein TypA/BipA; Derived by automated computational analysis using gene prediction method- Protein Homology (607 aa)
     
   
  0.612
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (142 aa)
     
        0.609
cbpA
Curved DNA-binding protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM (305 aa)
           
  0.606
JG24_28045
Binds single-stranded DNA at the primosome assembly site; Derived by automated computational analysis using gene prediction method- Protein Homology (104 aa)
   
        0.596
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (149 aa)
   
     
  0.596
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11 (293 aa)
   
      0.574
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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