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tsaC protein (Klebsiella pneumoniae) - STRING interaction network
"tsaC" - Threonylcarbamoyl-AMP synthase in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tsaCThreonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate (190 aa)    
Predicted Functional Partners:
JG24_23320
Similar to C-terminal Zn-finger domain of DNA topoisomerase I; Derived by automated computational analysis using gene prediction method- Protein Homology (180 aa)
 
   
  0.972
JG24_23330
Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake; Derived by automated computational analysis using gene prediction method- Protein Homology (374 aa)
 
        0.950
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (272 aa)
   
 
  0.922
JG24_23305
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (85 aa)
   
   
  0.873
smg
Protein Smg; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Smg family (157 aa)
              0.823
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (315 aa)
   
   
  0.815
JG24_21830
Universal genome maintenance protein; Kae1/Qri7/OSGEP/YgjD family protein; in Archaea, some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex; kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32); in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32; the protein is essential in Escherichia coli and Bacillus subtilis; Derived by automated computational analysis using gene prediction method- Protein Homology (337 aa)
 
   
  0.795
JG24_15680
Inactive homolog of metal-dependent proteases,putative molecular chaperone; Derived by automated computational analysis using gene prediction method- Protein Homology (231 aa)
 
   
  0.738
JG24_23345
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA (431 aa)
 
   
  0.738
JG24_15140
HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; Derived by automated computational analysis using gene prediction method- Protein Homology (282 aa)
   
  0.732
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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