STRINGSTRING
tusC protein (Klebsiella pneumoniae) - STRING interaction network
"tusC" - Protein TusC in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
tusCProtein TusC; Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (119 aa)    
Predicted Functional Partners:
JG24_23550
tRNA 5-methylaminomethyl-2-thiouridine synthase TusD; In Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; Derived by automated computational analysis using gene prediction method- Protein Homology (128 aa)
  0.999
JG24_23540
Protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (95 aa)
 
 
  0.999
JG24_23555
YheO-like PAS domain; Derived by automated computational analysis using gene prediction method- Protein Homology (240 aa)
 
        0.931
JG24_07475
Sulfurtransferase; Part of a sulfur-relay system (109 aa)
 
     
  0.818
JG24_15100
Putative ACR protein; Derived by automated computational analysis using gene prediction method- Protein Homology (117 aa)
   
 
  0.694
JG24_24105
TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; Derived by automated computational analysis using gene prediction method- Protein Homology (81 aa)
 
     
  0.687
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (124 aa)
              0.659
JG24_23560
Peptidyl-prolyl cis-trans isomerase; Rotamase; Derived by automated computational analysis using gene prediction method- Protein Homology (276 aa)
              0.617
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (482 aa)
 
     
  0.590
ygfZ
Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress; Physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulato; Hda supressor; Derived by automated computational [...] (327 aa)
   
     
  0.521
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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