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cysG protein (Klebsiella pneumoniae) - STRING interaction network
"cysG" - Siroheme synthase in Klebsiella pneumoniae
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (457 aa)    
Predicted Functional Partners:
hemD
Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (246 aa)
   
 
  0.972
JG24_20460
Catalyzes the formation of precorrin-3A from precorrin-2; Derived by automated computational analysis using gene prediction method- Protein Homology (236 aa)
 
 
  0.972
hemC
Transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (313 aa)
   
  0.968
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)
   
 
  0.960
JG24_20465
Derived by automated computational analysis using gene prediction method- Protein Homology (264 aa)
 
   
    0.944
JG24_20125
Derived by automated computational analysis using gene prediction method- Protein Homology (471 aa)
 
 
0.934
JG24_15070
Derived by automated computational analysis using gene prediction method- Protein Homology (957 aa)
 
   
  0.928
JG24_26495
Homolog of E. coli HemX protein; Derived by automated computational analysis using gene prediction method- Protein Homology (393 aa)
     
 
  0.913
JG24_03520
Hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; Derived by automated computational analysis using gene prediction method- Protein Homology (564 aa)
 
 
  0.892
JG24_20140
Sulfite reductase [NADPH] hemoprotein beta-component; Hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; Derived by automated computational analysis using gene prediction method- Protein Homology (570 aa)
 
 
  0.891
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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