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JG24_23760 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_23760" - FIG001957: putative hydrolase in Klebsiella pneumoniae
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
JG24_23760FIG001957- putative hydrolase; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)    
Predicted Functional Partners:
JG24_13520
Adenosine deaminase; Derived by automated computational analysis using gene prediction method- Protein Homology (333 aa)
         
  0.960
ushA
UDP-sugar hydrolase 5’-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the 5’-nucleotidase family (550 aa)
       
  0.921
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (432 aa)
   
    0.912
JG24_21680
3’,5’-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5’-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (275 aa)
   
   
    0.912
JG24_05775
Derived by automated computational analysis using gene prediction method- Protein Homology (216 aa)
       
  0.909
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis (264 aa)
       
  0.908
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily (152 aa)
     
 
  0.905
cpdB
2’,3’-cyclic-nucleotide 2’-phosphodiesterase; Periplasmic enzyme; functions during ribonucleic acid degradation; 2’,3’-cyclic nucleotides are first converted to 3’-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the 5’-nucleotidase family (647 aa)
       
  0.905
JG24_18715
Inosine-5’-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (488 aa)
       
    0.905
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis (294 aa)
       
  0.905
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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