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ompR protein (Klebsiella pneumoniae) - STRING interaction network
"ompR" - Part of two-component system EnvZ/OmpR in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ompRPart of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method- Protein Homology (239 aa)    
Predicted Functional Partners:
envZ
Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method- Protein Homology (451 aa)
  0.999
cpxA
Copper sensory histidine kinase CpxA; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method- Protein Homology (457 aa)
 
  0.837
phoR
Phosphate regulon sensor protein PhoR (SphS); Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method- Protein Homology (431 aa)
 
  0.828
JG24_22980
Aerobic respiration control sensor protein arcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method- Protein Homology (779 aa)
 
  0.744
JG24_20205
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method- Protein Homology (916 aa)
 
  0.718
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
   
 
  0.710
rcsB
Transcriptional regulatory protein RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions (216 aa)
   
 
 
  0.652
sirA
BarA-associated response regulator UvrY (= GacA = SirA); In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method- Protein Homology (218 aa)
   
 
  0.645
rcsC
Sensor histidine kinase RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB (946 aa)
 
  0.643
JG24_22255
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Derived by automated computational analysis using gene prediction method- Protein Homology (1080 aa)
   
 
0.642
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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