STRINGSTRING
nikR protein (Klebsiella pneumoniae) - STRING interaction network
"nikR" - Nickel-responsive regulator in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nikRNickel-responsive regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel (132 aa)    
Predicted Functional Partners:
nikE
Nickel transport ATP-binding protein NikE (TC 3.A.1.5.3); With NikABCD is involved with nickel transport into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (263 aa)
 
     
  0.962
nikD
Nickel ABC transporter ATP-binding protein; With NikABCE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (254 aa)
 
     
  0.960
nikC
Nickel transporter permease NikC; With NikABDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (277 aa)
         
  0.939
JG24_24175
Derived by automated computational analysis using gene prediction method- Protein Homology (522 aa)
 
     
  0.910
JG24_24180
With NikACDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (314 aa)
     
 
  0.880
JG24_16475
Derived by automated computational analysis using gene prediction method- Protein Homology (110 aa)
   
 
  0.722
JG24_15095
Response regulator NasT; Derived by automated computational analysis using gene prediction method- Protein Homology (393 aa)
           
  0.585
putA
Transcriptional regulator; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; Derived by automated computational analysis using gene prediction method- Protein Homology (1320 aa)
         
  0.582
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5’-adenylate (BirA-bio- 5’-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon (320 aa)
         
  0.546
JG24_19780
Derived by automated computational analysis using gene prediction method- Protein Homology (337 aa)
         
  0.537
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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