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mtlD protein (Klebsiella pneumoniae) - STRING interaction network
"mtlD" - Mannitol-1-phosphate 5-dehydrogenase in Klebsiella pneumoniae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (382 aa)    
Predicted Functional Partners:
JG24_24710
Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms the translocation channel and contains the specific substrate-binding site; subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method- Protein Homology (635 aa)
 
  0.998
mtlR
Acts as a repressor of the mtlAD operon; Derived by automated computational analysis using gene prediction method- Protein Homology (199 aa)
 
   
  0.984
JG24_19740
Sorbitol-6-phosphate 2-dehydrogenase; Catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family (259 aa)
   
   
  0.922
JG24_19930
ROK family Glucokinase with ambiguous substrate specificity; Derived by automated computational analysis using gene prediction method- Protein Homology (304 aa)
     
  0.919
JG24_03940
Glucokinase, ROK family; Catalyzes phosphorylation of fructose; cytosolic enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (304 aa)
     
  0.919
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (320 aa)
 
   
  0.918
JG24_10655
Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (392 aa)
       
  0.908
JG24_12330
Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method- Protein Homology (226 aa)
         
  0.905
JG24_04925
Derived by automated computational analysis using gene prediction method- Protein Homology (307 aa)
       
  0.903
JG24_25915
6-phosphofructokinase; Derived by automated computational analysis using gene prediction method- Protein Homology (326 aa)
       
  0.903
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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