STRINGSTRING
srkA protein (Klebsiella pneumoniae) - STRING interaction network
"srkA" - Stress response kinase A in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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srkAStress response kinase A; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response (328 aa)    
Predicted Functional Partners:
JG24_25790
Thiol-disulfide interchange protein; Derived by automated computational analysis using gene prediction method- Protein Homology (207 aa)
 
   
  0.960
JG24_25780
Protein yihD; Derived by automated computational analysis using gene prediction method- Protein Homology (89 aa)
              0.676
JG24_29705
Has polymerase, DNA-binding and 3’-5’ exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method- Protein Homology (785 aa)
   
          0.612
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
         
  0.609
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family (193 aa)
              0.455
JG24_25770
Molybdopterin-guanine dinucleotide biosynthesis protein MobB; In Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; Derived by automated computational analysis using gene prediction method- Protein Homology (168 aa)
              0.455
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5’-CTGTATATATATACAG-3’. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (202 aa)
   
        0.447
slmA
Transcriptional regulator SlmA, TetR family; FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; Derived by automated computational analysis using gene prediction method- Protein Homology (198 aa)
   
          0.422
sbcB
Exonucleolytic cleavage in the 3’- to 5’-direction to yield nucleoside 5’-phosphates; Derived by automated computational analysis using gene prediction method- Protein Homology (472 aa)
   
          0.418
JG24_17990
DedD protein; Derived by automated computational analysis using gene prediction method- Protein Homology (231 aa)
   
          0.416
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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