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dtd protein (Klebsiella pneumoniae) - STRING interaction network
"dtd" - D-aminoacyl-tRNA deacylase in Klebsiella pneumoniae
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dtdD-aminoacyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl- tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality; Belongs to the DTD family (145 aa)    
Predicted Functional Partners:
JG24_25845
Probable haloacid dehalogenase-like hydrolase STY3852; Derived by automated computational analysis using gene prediction method- Protein Homology (199 aa)
            0.926
JG24_25860
Galactoside O-acetyltransferase, probable YiiD; Derived by automated computational analysis using gene prediction method- Protein Homology (313 aa)
 
   
  0.908
JG24_25850
UPF0761 membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (286 aa)
   
        0.887
JG24_25840
GTP-binding protein TypA/BipA; Derived by automated computational analysis using gene prediction method- Protein Homology (607 aa)
              0.652
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (240 aa)
 
     
  0.612
JG24_06145
4-hydroxybenzoyl-CoA thioesterase family active site; Catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; Derived by automated computational analysis using gene prediction method- Protein Homology (134 aa)
           
  0.528
JG24_07195
Derived by automated computational analysis using gene prediction method- Protein Homology (754 aa)
 
     
  0.476
JG24_13680
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (135 aa)
         
  0.475
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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