STRINGSTRING
JG24_26145 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_26145" - Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JG24_26145Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method- Protein Homology (386 aa)    
Predicted Functional Partners:
metL
Homoserine dehydrogenase; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method- Protein Homology (810 aa)
 
 
  0.985
JG24_21515
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (456 aa)
  0.985
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
   
 
  0.966
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine; Belongs to the MetA family (309 aa)
 
 
  0.963
JG24_18315
Cysteine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family (323 aa)
  0.950
cysM
Cysteine synthase B; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method- Protein Homology (303 aa)
  0.944
JG24_21595
Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method- Protein Homology (395 aa)
   
 
0.940
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (754 aa)
 
 
  0.939
JG24_04310
Cysteine synthase B; Derived by automated computational analysis using gene prediction method- Protein Homology (350 aa)
 
  0.929
JG24_14715
Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method- Protein Homology (343 aa)
   
 
  0.928
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
Server load: low (8%) [HD]