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JG24_26225 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_26225" - Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
JG24_26225Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; Derived by automated computational analysis using gene prediction method- Protein Homology (305 aa)    
Predicted Functional Partners:
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (467 aa)
       
 
  0.718
JG24_09840
Derived by automated computational analysis using gene prediction method- Protein Homology (295 aa)
   
   
  0.678
JG24_05670
Alkyl hydroperoxide reductase protein F; Derived by automated computational analysis using gene prediction method- Protein Homology (521 aa)
         
  0.642
JG24_12810
Peroxidase; Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily (725 aa)
         
  0.609
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide (752 aa)
         
  0.609
JG24_27340
Redox-sensitive transcriptional activator SoxR; Derived by automated computational analysis using gene prediction method- Protein Homology (152 aa)
       
 
  0.557
JG24_19965
Transcriptional regulatory protein; Derived by automated computational analysis using gene prediction method- Protein Homology (295 aa)
   
          0.548
JG24_24255
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (450 aa)
         
  0.540
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; Derived by automated computational analysis using gene prediction method- Protein Homology (330 aa)
           
  0.533
JG24_00895
Derived by automated computational analysis using gene prediction method- Protein Homology (300 aa)
   
     
  0.529
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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