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sthA protein (Klebsiella pneumoniae) - STRING interaction network
"sthA" - Soluble pyridine nucleotide transhydrogenase in Klebsiella pneumoniae
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sthASoluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (466 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source (275 aa)
   
    0.911
JG24_05775
Derived by automated computational analysis using gene prediction method- Protein Homology (216 aa)
         
  0.910
nudC
NADH pyrophosphatase; Can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5’-phosphates; Derived by automated computational analysis using gene prediction method- Protein Homology (257 aa)
     
 
  0.906
JG24_29350
Catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside; also has a regulatory function; Derived by automated computational analysis using gene prediction method- Protein Homology (410 aa)
         
    0.900
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method- Protein Homology (263 aa)
         
    0.900
pntB
NAD(P) transhydrogenase subunit beta; Catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; Derived by automated computational analysis using gene prediction method- Protein Homology (462 aa)
     
 
  0.890
pntA
NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (509 aa)
         
  0.844
ppnK
Inorganic polyphosphate kinase; Catalyzes the phosphorylation of NAD to NADP; Derived by automated computational analysis using gene prediction method- Protein Homology (292 aa)
         
  0.824
JG24_03495
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method- Protein Homology (511 aa)
 
  0.691
JG24_06110
Component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; Derived by automated computational analysis using gene prediction method- Protein Homology (408 aa)
 
  0.691
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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