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btuB protein (Klebsiella pneumoniae) - STRING interaction network
"btuB" - Outer membrane vitamin B12 receptor BtuB in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
btuBOuter membrane vitamin B12 receptor BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; Derived by automated computational analysis using gene prediction method- Protein Homology (612 aa)    
Predicted Functional Partners:
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis (283 aa)
         
  0.900
JG24_14885
Ferric siderophore transport system, periplasmic binding protein TonB; Derived by automated computational analysis using gene prediction method- Protein Homology (248 aa)
   
 
  0.799
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
 
     
  0.773
JG24_30330
Vitamin B12 ABC transporter, B12-binding component BtuF; Solute binding component of the vitamin B12 transport system BtuCDF; Derived by automated computational analysis using gene prediction method- Protein Homology (266 aa)
 
   
  0.754
JG24_09545
Cob(I)alamin adenosyltransferase; Catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin; Derived by automated computational analysis using gene prediction method- Protein Homology (196 aa)
   
  0.752
JG24_27010
L-sorbose 1-phosphate reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (410 aa)
           
  0.646
JG24_06150
MotA/TolQ/ExbB proton channel family protein; Membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
 
 
  0.628
tolB
Protein TolB; Involved in the TonB-independent uptake of proteins (430 aa)
           
  0.620
JG24_14785
ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; Derived by automated computational analysis using gene prediction method- Protein Homology (249 aa)
   
 
 
  0.611
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family (105 aa)
           
  0.573
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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