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rhlB protein (Klebsiella pneumoniae) - STRING interaction network
"rhlB" - ATP-dependent RNA helicase RhlB in Klebsiella pneumoniae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA; Belongs to the DEAD box helicase family. RhlB subfamily (421 aa)    
Predicted Functional Partners:
rraA
Regulator of ribonuclease activity A; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (161 aa)
       
 
  0.588
JG24_26380
Guanosine-5’-triphosphate,3’-diphosphate pyrophosphatase @ Exopolyphosphatase; Catalyzes the conversion of guanosine 5’-triphosphate,3’-diphosphate (pppGpp) to guanosine 5’-diphosphate,3’-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; Derived by automated computational analysis using gene prediction method- Protein Homology (499 aa)
 
        0.573
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (102 aa)
       
 
  0.566
nnrD
ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (508 aa)
   
 
  0.559
JG24_22735
Polyribonucleotide nucleotidyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (711 aa)
   
 
  0.538
JG24_26375
LysR-family transcriptional regulator; Derived by automated computational analysis using gene prediction method- Protein Homology (308 aa)
     
      0.536
proQ
RNA chaperone ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism (225 aa)
     
   
  0.533
JG24_07370
ABC transporter ATP-binding protein uup; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method- Protein Homology (635 aa)
 
      0.522
rne
Bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; Derived by automated computational analysis using gene prediction method- Protein Homology (1082 aa)
     
 
  0.498
JG24_04695
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (164 aa)
 
 
 
  0.496
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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