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trxA protein (Klebsiella pneumoniae) - STRING interaction network
"trxA" - Thioredoxin in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
trxAThioredoxin; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the thioredoxin family (109 aa)    
Predicted Functional Partners:
JG24_07085
Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family (322 aa)
 
 
  0.990
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho’s RNA-dependent ATPase activity, and release of the mRNA from the DNA template (419 aa)
 
   
  0.912
gltB
Glutamate synthase [NADPH] large chain; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology (1486 aa)
       
      0.854
gshA
Glutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily (518 aa)
     
   
  0.767
dnaK
Chaperone protein DnaK; Acts as a chaperone (638 aa)
 
 
  0.752
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (176 aa)
           
  0.672
groEL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (548 aa)
 
 
  0.615
JG24_04710
Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (288 aa)
   
 
 
  0.609
bcp
Thiol peroxidase, Bcp-type; Bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; Derived by automated computational analysis using gene prediction method- Protein Homology (156 aa)
     
 
  0.593
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily (244 aa)
       
 
  0.572
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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