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wecA protein (Klebsiella pneumoniae) - STRING interaction network
"wecA" - Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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wecAUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) (367 aa)    
Predicted Functional Partners:
JG24_26405
Regulator of length of O-antigen component of lipopolysaccharide chains; Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; Derived by automated computational analysis using gene prediction method- Protein Homology (348 aa)
   
  0.982
JG24_26410
UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family (361 aa)
   
  0.966
wecC
UDP-glucose dehydrogenase; Catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; Derived by automated computational analysis using gene prediction method- Protein Homology (420 aa)
   
   
  0.833
wzxE
Lipid III flippase; Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family (416 aa)
 
   
  0.824
JG24_26455
Probable UDP-N-acetyl-D-mannosaminuronic acid transferase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the glycosyltransferase 26 family (246 aa)
 
 
 
  0.804
JG24_26430
Lipopolysaccharide biosynthesis protein RffC; Derived by automated computational analysis using gene prediction method- Protein Homology (224 aa)
 
   
  0.797
JG24_16900
Polysaccharide export lipoprotein Wza; Required for the translocation of capsular polysaccharide through the outer membrane; Derived by automated computational analysis using gene prediction method- Protein Homology (377 aa)
       
  0.783
JG24_26450
Putative ECA polymerase; Enterobacterial common antigen polymerase; Derived by automated computational analysis using gene prediction method- Protein Homology (448 aa)
 
     
  0.728
uppS
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide (252 aa)
   
 
  0.705
rffT
TDP-N-acetylfucosamine-lipid II N-acetylfucosaminyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family (358 aa)
 
   
  0.691
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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