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ubiA protein (Klebsiella pneumoniae) - STRING interaction network
"ubiA" - 4-hydroxybenzoate octaprenyltransferase in Klebsiella pneumoniae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate (288 aa)    
Predicted Functional Partners:
ubiC
Chorismate--pyruvate lyase; Catalyzes the formation of 4-hydroxybenzoate from chorismate; Derived by automated computational analysis using gene prediction method- Protein Homology (165 aa)
 
 
  0.993
JG24_26680
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UbiD family (489 aa)
 
  0.974
JG24_20040
Probable UbiX-like flavin prenyltransferase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C. Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (197 aa)
 
 
  0.965
ubiX
Flavin prenyltransferase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN (194 aa)
 
 
  0.965
JG24_08825
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method- Protein Homology (500 aa)
 
 
  0.941
JG24_22870
Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPP/GGPP synthase family (323 aa)
 
 
  0.937
JG24_17660
3-demethylubiquinol 3-O-methyltransferase; Involved in ubiquinone biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (242 aa)
 
 
  0.901
JG24_21275
Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; Derived by automated computational analysis using gene prediction method- Protein Homology (392 aa)
   
   
  0.879
ubiE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (251 aa)
 
 
 
  0.845
ubiB
Probable protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis (546 aa)
 
 
  0.820
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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