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JG24_28485 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_28485" - 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA in Klebsiella pneumoniae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JG24_284853’,5’-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5’-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (274 aa)    
Predicted Functional Partners:
JG24_28475
Glycerol-3-phosphate-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology (436 aa)
          0.988
cyaA
Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3’-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the adenylyl cyclase class-1 family (850 aa)
         
  0.969
JG24_28490
Putative SN-glycerol-3-phosphate transport system permease; Derived by automated computational analysis using gene prediction method- Protein Homology (295 aa)
 
          0.938
JG24_28495
N-Acetyl-D-glucosamine ABC transport system,permease protein; Derived by automated computational analysis using gene prediction method- Protein Homology (290 aa)
 
          0.924
ushA
UDP-sugar hydrolase 5’-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the 5’-nucleotidase family (550 aa)
       
  0.912
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method- Protein Homology (263 aa)
     
 
    0.905
JG24_08440
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines- the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (456 aa)
   
 
    0.903
surE
5’/3’-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5’- monophosphates and ribonucleoside 3’-monophosphates with highest affinity to 3’-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3’-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (253 aa)
     
 
    0.902
JG24_20255
Decarboxylase family protein; Derived by automated computational analysis using gene prediction method- Protein Homology (455 aa)
     
 
    0.901
JG24_13755
Cytokinin riboside 5’-monophosphate phosphoribohydrolase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the LOG family (192 aa)
     
 
    0.901
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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