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thrA protein (Klebsiella pneumoniae) - STRING interaction network
"thrA" - Aspartokinase / Homoserine dehydrogenase in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
thrAAspartokinase / Homoserine dehydrogenase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method- Protein Homology (820 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily (309 aa)
  0.999
JG24_29430
Threonine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (426 aa)
 
 
  0.998
JG24_23915
Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family (368 aa)
   
  0.982
JG24_12525
Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family (372 aa)
   
  0.980
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
   
 
  0.970
JG24_18585
Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the DapA family (292 aa)
   
 
  0.966
JG24_11690
Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the DapA family (294 aa)
   
 
  0.965
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine; Belongs to the MetA family (309 aa)
 
  0.963
asnB
Asparagine synthetase [glutamine-hydrolyzing]; Functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; Derived by automated computational analysis using gene prediction method- Protein Homology (554 aa)
 
 
  0.938
JG24_12725
Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family (460 aa)
       
  0.924
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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