STRINGSTRING
thrB protein (Klebsiella pneumoniae) - STRING interaction network
"thrB" - Homoserine kinase in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily (309 aa)    
Predicted Functional Partners:
JG24_29430
Threonine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (426 aa)
 
  0.999
thrA
Aspartokinase / Homoserine dehydrogenase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method- Protein Homology (820 aa)
  0.999
metL
Homoserine dehydrogenase; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method- Protein Homology (810 aa)
  0.998
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; One of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; Derived by automated computational analysis using gene prediction method- Protein Homology (1227 aa)
   
 
  0.924
JG24_26145
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method- Protein Homology (386 aa)
   
 
  0.857
JG24_21520
Cystathionine gamma-lyase; Derived by automated computational analysis using gene prediction method- Protein Homology (382 aa)
   
 
  0.857
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (309 aa)
   
 
  0.850
JG24_21515
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (456 aa)
         
  0.846
JG24_21595
Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method- Protein Homology (395 aa)
   
 
  0.846
JG24_03805
Derived by automated computational analysis using gene prediction method- Protein Homology (310 aa)
         
  0.835
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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