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lspA protein (Klebsiella pneumoniae) - STRING interaction network
"lspA" - Lipoprotein signal peptidase in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Experiments
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Textmining
[Homology]
Score
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family (166 aa)    
Predicted Functional Partners:
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (938 aa)
   
  0.988
JG24_29525
Peptidyl-prolyl cis-trans isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method- Protein Homology (149 aa)
 
   
  0.935
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis (316 aa)
 
        0.918
JG24_29510
Riboflavin biosynthesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ribF family (312 aa)
 
   
  0.863
JG24_22880
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (419 aa)
 
 
  0.735
murJ
Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (511 aa)
 
   
  0.690
murG
UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; N-acetylglucosaminyl transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (356 aa)
 
   
  0.652
JG24_18975
Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S26 family (324 aa)
 
   
  0.648
ribD
5-amino-6-(5-phosphoribosylamino)uracil reductase; Riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; Derived by automated computational analysis using gene prediction method- Protein Homology (367 aa)
         
  0.631
secG
Preprotein translocase subunit SecG (TC 3.A.5.1.1); Derived by automated computational analysis using gene prediction method- Protein Homology (109 aa)
   
   
  0.616
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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