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JG24_29705 protein (Klebsiella pneumoniae) - STRING interaction network
"JG24_29705" - Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
JG24_29705Has polymerase, DNA-binding and 3’-5’ exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method- Protein Homology (785 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
     
 
  0.877
rapA
RNA polymerase-associated protein RapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (968 aa)
 
  0.846
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose (500 aa)
            0.819
JG24_25485
DNA polymerase III beta subunit; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method- Protein Homology (366 aa)
   
 
  0.751
JG24_29700
Derived by automated computational analysis using gene prediction method- Protein Homology (59 aa)
              0.720
JG24_29690
Catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; Derived by automated computational analysis using gene prediction method- Protein Homology (219 aa)
   
        0.716
JG24_19555
Ribonucleotide reductase of class Ib (Aerobic),alpha subunit; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (713 aa)
     
 
  0.701
JG24_17665
Ribonucleotide reductase of class Ia (Aerobic),alpha subunit; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (761 aa)
     
 
  0.701
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3’-5’ exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (351 aa)
     
 
  0.695
srkA
Stress response kinase A; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response (328 aa)
   
          0.612
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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