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murD protein (Klebsiella pneumoniae) - STRING interaction network
"murD" - UDP-N-acetylmuramoylalanine--D-glutamate ligase in Klebsiella pneumoniae
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; Derived by automated computational analysis using gene prediction method- Protein Homology (438 aa)    
Predicted Functional Partners:
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; Derived by automated computational analysis using gene prediction method- Protein Homology (495 aa)
 
0.996
murG
UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; N-acetylglucosaminyl transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (356 aa)
   
  0.996
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family (491 aa)
0.992
mraY
Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily (360 aa)
   
  0.991
ftsW
Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily (424 aa)
   
  0.981
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis (283 aa)
 
 
  0.979
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily (452 aa)
   
0.973
JG24_29865
Cell division protein FtsI [Peptidoglycan synthetase]; Penicillin-binding protein 3; transpeptidase involved in septal peptidoglycan synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (588 aa)
 
  0.958
rsmH
Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (313 aa)
 
   
  0.943
mraZ
Transcriptional regulator MraZ; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster (152 aa)
 
   
  0.940
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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