STRINGSTRING
secM protein (Klebsiella pneumoniae) - STRING interaction network
"secM" - Secretion monitor in Klebsiella pneumoniae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secMSecretion monitor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (167 aa)    
Predicted Functional Partners:
secA
Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family (901 aa)
 
   
  0.919
JG24_25450
Outer membrane lipoprotein YidQ; Derived by automated computational analysis using gene prediction method- Protein Homology (110 aa)
   
          0.753
JG24_20105
Putative cytochrome oxidase subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (108 aa)
   
          0.725
thiK
Catalyzes the phosphorylation of thiamine to thiamine phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (275 aa)
   
 
      0.723
bssS
Putative cytoplasmic protein; BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; Derived by automated computational analysis using gene prediction method- Protein Homology (84 aa)
   
          0.723
JG24_17440
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (114 aa)
   
          0.715
JG24_18905
Putative alpha helix protein; Derived by automated computational analysis using gene prediction method- Protein Homology (228 aa)
   
          0.713
JG24_24085
Putative inner membrane protein; Derived by automated computational analysis using gene prediction method- Protein Homology (91 aa)
   
          0.707
JG24_26910
Derived by automated computational analysis using gene prediction method- Protein Homology (231 aa)
   
          0.704
JG24_11390
UPF0482 protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0482 family (113 aa)
   
          0.704
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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