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pdhR protein (Klebsiella pneumoniae) - STRING interaction network
"pdhR" - Transcriptional repressor for pyruvate dehydrogenase complex in Klebsiella pneumoniae
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pdhRTranscriptional repressor for pyruvate dehydrogenase complex; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method- Protein Homology (259 aa)    
Predicted Functional Partners:
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (887 aa)
 
 
  0.742
JG24_24735
L-lactate permease; Derived by automated computational analysis using gene prediction method- Protein Homology (551 aa)
 
   
  0.715
aceF
E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; Derived by automated computational analysis using gene prediction method- Protein Homology (632 aa)
   
 
  0.697
fadR
Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism (239 aa)
   
     
  0.664
sdhA
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily (588 aa)
           
  0.527
frdC
Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (131 aa)
           
  0.525
JG24_30035
Dihydrolipoyl dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method- Protein Homology (474 aa)
     
 
  0.519
sdhC
Succinate dehydrogenase cytochrome b-556 subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (134 aa)
   
   
  0.506
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (321 aa)
           
  0.486
purH
Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (529 aa)
           
  0.428
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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