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erpA protein (Klebsiella pneumoniae) - STRING interaction network
"erpA" - Iron-sulfur cluster insertion protein ErpA in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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erpAIron-sulfur cluster insertion protein ErpA; Essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; Derived by automated computational analysis using gene prediction method- Protein Homology (114 aa)    
Predicted Functional Partners:
hscA
Chaperone protein HscA; Involved in the maturation of iron-sulfur cluster-containing proteins; Derived by automated computational analysis using gene prediction method- Protein Homology (616 aa)
 
 
  0.868
JG24_16675
Derived by automated computational analysis using gene prediction method- Protein Homology (279 aa)
   
 
  0.751
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (321 aa)
 
   
  0.743
JG24_30315
H(+)/Cl(-) exchange transporter ClcA; Derived by automated computational analysis using gene prediction method- Protein Homology (472 aa)
         
  0.720
ygfZ
Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress; Physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulato; Hda supressor; Derived by automated computational [...] (327 aa)
 
 
  0.705
JG24_18840
Iron-sulfur cluster regulator IscR; Regulates the expression of the iscRSUA operon; Derived by automated computational analysis using gene prediction method- Protein Homology (163 aa)
 
 
  0.675
hscB
Co-chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (171 aa)
 
 
  0.674
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins (191 aa)
   
 
  0.638
JG24_18830
Iron-sulfur cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (128 aa)
 
   
  0.629
JG24_14635
Iron-sulfur cluster assembly protein SufD; With SufBC activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method- Protein Homology (424 aa)
   
 
  0.627
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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