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dgt protein (Klebsiella pneumoniae) - STRING interaction network
"dgt" - dGTPase in Klebsiella pneumoniae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dgtdGTPase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs (504 aa)    
Predicted Functional Partners:
surE
5’/3’-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5’- monophosphates and ribonucleoside 3’-monophosphates with highest affinity to 3’-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3’-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (253 aa)
   
 
  0.928
deoD
Purine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2’- deoxyribonucleosides to the free base and (2’-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology (239 aa)
         
  0.915
JG24_29280
Manganese-dependent 5’-nucleotidase; specific for 5’-UMP, 5’-dUMP, and 5’-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; Derived by automated computational analysis using gene prediction method- Protein Homology (225 aa)
       
  0.915
JG24_23760
FIG001957- putative hydrolase; Derived by automated computational analysis using gene prediction method- Protein Homology (227 aa)
       
  0.904
JG24_15930
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (480 aa)
     
 
    0.902
JG24_14610
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology (470 aa)
     
 
    0.902
JG24_18770
Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the NDK family (143 aa)
     
 
    0.900
JG24_28330
Ribonucleotide reductase of class III (Anaerobic), large subunit; Catalyzes the reduction of nucleoside 5’-triphosphates to 2’-deoxynucleoside 5’-triphosphates; Derived by automated computational analysis using gene prediction method- Protein Homology (712 aa)
         
    0.900
ushA
UDP-sugar hydrolase 5’-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the 5’-nucleotidase family (550 aa)
         
    0.900
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (930 aa)
   
   
  0.705
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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