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dapD protein (Klebsiella pneumoniae) - STRING interaction network
"dapD" - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase in Klebsiella pneumoniae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the transferase hexapeptide repeat family (274 aa)    
Predicted Functional Partners:
dapB
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (273 aa)
 
 
  0.998
JG24_23630
Acetylornithine aminotransferase / N-succinyl-L,L-diaminopimelate aminotransferase; DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; Derived by automated computational analysis using gene prediction method- Protein Homology (406 aa)
   
 
  0.919
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism (887 aa)
       
  0.830
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (420 aa)
 
   
  0.818
JG24_18585
Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the DapA family (292 aa)
 
   
  0.761
JG24_18015
Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family (337 aa)
 
   
  0.757
JG24_23915
Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family (368 aa)
   
   
  0.735
JG24_18550
N-succinyl-L,L-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method- Protein Homology (375 aa)
 
   
  0.729
JG24_27070
Aspartokinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; Derived by automated computational analysis using gene prediction method- Protein Homology (449 aa)
 
   
  0.725
thrA
Aspartokinase / Homoserine dehydrogenase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method- Protein Homology (820 aa)
 
   
  0.719
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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