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uppS protein (Klebsiella pneumoniae) - STRING interaction network
"uppS" - Ditrans,polycis-undecaprenyl-diphosphate synthase in Klebsiella pneumoniae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
uppSDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide (252 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the CDS family (285 aa)
 
   
  0.973
JG24_04130
Derived by automated computational analysis using gene prediction method- Protein Homology (299 aa)
 
  0.967
JG24_22870
Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPP/GGPP synthase family (323 aa)
 
  0.953
JG24_30395
1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP); Belongs to the DXR family (400 aa)
 
 
  0.892
JG24_30410
Zinc metalloprotease; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method- Protein Homology (450 aa)
 
        0.878
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family (273 aa)
 
     
  0.838
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; Derived by automated computational analysis using gene prediction method- Protein Homology (495 aa)
 
 
 
  0.834
murG
UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; N-acetylglucosaminyl transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (356 aa)
 
 
  0.825
bamA
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery (809 aa)
   
   
  0.747
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation (342 aa)
 
   
  0.724
Your Current Organism:
Klebsiella pneumoniae
NCBI taxonomy Id: 573
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633
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