STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG12724.1PFAM: ATP dependent DNA ligase; KEGG: mfe:Mefer_1305 ATP dependent DNA ligase. (388 aa)    
Predicted Functional Partners:
ADG13323.1
Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.800
ribL
Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
       0.782
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.773
mfnA
Pyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
       0.773
ADG12726.1
Nitrogenase; KEGG: mmp:MMP0147 nitrogenase reductase-like protein; PFAM: NifH/frxC-family protein; Belongs to the NifH/BchL/ChlL family.
       0.773
ADG12727.1
PFAM: protein of unknown function DUF34; KEGG: mja:MJ0927 hypothetical protein.
       0.773
ADG12721.1
PFAM: protein of unknown function UPF0118; KEGG: mvu:Metvu_0384 protein of unknown function UPF0118.
       0.752
ADG13074.1
PFAM: Protein of unknown function DUF61; KEGG: mfe:Mefer_0582 protein of unknown function DUF61; Belongs to the UPF0216 family.
  
     0.635
ADG13898.1
SMART: DNA-directed DNA polymerase B; TIGRFAM: DNA polymerase Pol2; KEGG: mmq:MmarC5_1258 replicative DNA polymerase I; PFAM: DNA polymerase B region; DNA polymerase B exonuclease.
 
    0.574
ADG12719.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: mfe:Mefer_0929 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
       0.556
Your Current Organism:
Methanocaldococcus infernus
NCBI taxonomy Id: 573063
Other names: M. infernus ME, Methanocaldococcus infernus DSM 11812, Methanocaldococcus infernus ME, Methanocaldococcus infernus str. ME, Methanocaldococcus infernus strain ME
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