STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG12726.1Nitrogenase; KEGG: mmp:MMP0147 nitrogenase reductase-like protein; PFAM: NifH/frxC-family protein; Belongs to the NifH/BchL/ChlL family. (262 aa)    
Predicted Functional Partners:
ADG12709.1
Nitrogenase; KEGG: mvu:Metvu_1085 nitrogenase; PFAM: oxidoreductase/nitrogenase component 1.
 
 0.990
ADG12710.1
TIGRFAM: nitrogenase alpha chain; nitrogenase component I, alpha chain; KEGG: mvu:Metvu_1084 nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase component 1.
 
 0.989
ADG13107.1
TIGRFAM: glutamine synthetase, type I; KEGG: mja:MJ1346 glutamine synthetase (GlnA); PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
 
 0.971
ADG12705.1
PFAM: oxidoreductase/nitrogenase component 1; KEGG: mvu:Metvu_0866 oxidoreductase/nitrogenase component 1.
 
 0.925
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 
0.905
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.902
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
 0.898
ADG13425.1
PFAM: Protein of unknown function DUF128; Ribonuclease R winged-helix domain protein; KEGG: mja:MJ0159 hypothetical protein.
      
 0.890
nifB
Radical SAM domain protein; Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM- dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
 
  
 0.797
mfnA
Pyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
       0.776
Your Current Organism:
Methanocaldococcus infernus
NCBI taxonomy Id: 573063
Other names: M. infernus ME, Methanocaldococcus infernus DSM 11812, Methanocaldococcus infernus ME, Methanocaldococcus infernus str. ME, Methanocaldococcus infernus strain ME
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