node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACV24717.1 | cofC | Mefer_0899 | Mefer_1466 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.712 |
ACV24717.1 | cofD | Mefer_0899 | Mefer_0031 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.761 |
ACV24717.1 | cofE | Mefer_0899 | Mefer_1035 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | F420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.748 |
ACV24717.1 | cofG | Mefer_0899 | Mefer_0989 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.609 |
ACV24717.1 | mer | Mefer_0899 | Mefer_1535 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.709 |
ACV25038.1 | cofC | Mefer_1229 | Mefer_1466 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: mxa:MXAN_0352 ribosomal protein S6 modification protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.591 |
ACV25038.1 | cofD | Mefer_1229 | Mefer_0031 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: mxa:MXAN_0352 ribosomal protein S6 modification protein. | LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.872 |
ACV25038.1 | cofE | Mefer_1229 | Mefer_1035 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: mxa:MXAN_0352 ribosomal protein S6 modification protein. | F420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.902 |
ACV25269.1 | ACV25271.1 | Mefer_1465 | Mefer_1467 | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein. | 0.633 |
ACV25269.1 | ACV25272.1 | Mefer_1465 | Mefer_1468 | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein. | 0.604 |
ACV25269.1 | cofC | Mefer_1465 | Mefer_1466 | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.671 |
ACV25271.1 | ACV25269.1 | Mefer_1467 | Mefer_1465 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein. | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | 0.633 |
ACV25271.1 | ACV25272.1 | Mefer_1467 | Mefer_1468 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein. | KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein. | 0.779 |
ACV25271.1 | cofC | Mefer_1467 | Mefer_1466 | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.906 |
ACV25272.1 | ACV25269.1 | Mefer_1468 | Mefer_1465 | KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein. | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | 0.604 |
ACV25272.1 | ACV25271.1 | Mefer_1468 | Mefer_1467 | KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein. | TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; KEGG: bja:blr2308 putative molybdopterin biosynthesis protein. | 0.779 |
ACV25272.1 | cofC | Mefer_1468 | Mefer_1466 | KEGG: DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.779 |
cofC | ACV24717.1 | Mefer_1466 | Mefer_0899 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase. | 0.712 |
cofC | ACV25038.1 | Mefer_1466 | Mefer_1229 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: mxa:MXAN_0352 ribosomal protein S6 modification protein. | 0.591 |
cofC | ACV25269.1 | Mefer_1466 | Mefer_1465 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | PFAM: beta-lactamase domain protein; KEGG: sfu:Sfum_1958 beta-lactamase domain protein. | 0.671 |