STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (319 aa)    
Predicted Functional Partners:
ADL13363.1
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR018313:IPR015793:IPR 015794:IPR008279:IPR015813:IPR015795:IPR011037; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: B8D1K6 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.989
ADL13249.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterProIPR001249:IPR000089:IPR000891:IPR013785:IPR 003379:IPR001882:IPR011053; KEGG: chy:CHY_1999 pyruvate carboxylase subunit B; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; PRIAM: Pyruvate carboxylase; SPTR: Q3AAL6 Oxaloacetate decarboxylase, alpha subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain; TIGRFA [...]
    
 0.963
ADL11588.1
Pyruvate ferredoxin oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019775:IPR002880:IPR015941:IPR009014; KEGG: hor:Hore_20720 pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: B8CZW5 Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain.
  
 
 0.951
ADL12000.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR015941:IPR009014:IPR002880:IPR005476; KEGG: gsu:GSU1468 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: A8RJL6 Putative uncharacterized protein; PFAM: domain; Transketolase, C-terminal domain.
  
 
 0.951
ADL12228.1
Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR010121:IPR018274:IPR000121:IPR013815:IPR 013816:IPR008279:IPR015813:IPR002192; KEGG: chy:CHY_0443 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q3AEY0 Pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/p [...]
 
 
 0.943
ADL13381.1
L-aspartate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004838:IPR004839:IPR015424:IPR015421:IPR 001176; KEGG: cth:Cthe_0755 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A3DDG1 L-aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
 0.940
ADL11589.1
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: csc:Csac_1461 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A4XJH6 Thiamine pyrophosphate enzyme domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 
 0.932
ADL12001.1
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: nth:Nther_1483 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A8RJL7 Putative uncharacterized protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 
 0.932
ADL12063.1
Malate dehydrogenase (oxaloacetate-decarboxylating); COGs: COG0281 Malic enzyme; InterPro IPR016040:IPR015884:IPR012301:IPR012302; KEGG: bay:RBAM_026270 YtsJ; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: A7Z7K9 YtsJ; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 0.928
ADL12485.1
Malate dehydrogenase (oxaloacetate-decarboxylating); COGs: COG0281 Malic enzyme; InterProIPR015884:IPR016040:IPR012301:IPR012302:IPR 001891; KEGG: amt:Amet_2965 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: A6TSE7 Malate dehydrogenase (Oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 0.928
Your Current Organism:
Acetohalobium arabaticum
NCBI taxonomy Id: 574087
Other names: A. arabaticum DSM 5501, Acetohalobium arabaticum DSM 5501, Acetohalobium arabaticum str. DSM 5501, Acetohalobium arabaticum strain DSM 5501
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