node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_0185 | mutM | VS_0185 | VS_0186 | Hypothetical protein. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.800 |
VS_0185 | rpmB | VS_0185 | VS_0183 | Hypothetical protein. | Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. | 0.496 |
VS_1385 | VS_1954 | VS_1385 | VS_1954 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.453 |
VS_1385 | VS_1955 | VS_1385 | VS_1955 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.453 |
VS_1385 | mutM | VS_1385 | VS_0186 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.714 |
VS_1954 | VS_1385 | VS_1954 | VS_1385 | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.453 |
VS_1954 | VS_1955 | VS_1954 | VS_1955 | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.991 |
VS_1954 | mutM | VS_1954 | VS_0186 | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.631 |
VS_1954 | polA | VS_1954 | VS_0108 | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.628 |
VS_1955 | VS_1385 | VS_1955 | VS_1385 | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.453 |
VS_1955 | VS_1954 | VS_1955 | VS_1954 | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | Putative excinuclease ABC subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.991 |
VS_1955 | mutM | VS_1955 | VS_0186 | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.631 |
VS_1955 | polA | VS_1955 | VS_0108 | Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.608 |
VS_2551 | VS_2552 | VS_2551 | VS_2552 | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoaE family. | 0.524 |
VS_2551 | mutM | VS_2551 | VS_0186 | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.700 |
VS_2551 | nth | VS_2551 | VS_0971 | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.452 |
VS_2551 | polA | VS_2551 | VS_0108 | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.630 |
VS_2552 | VS_2551 | VS_2552 | VS_2551 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoaE family. | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. | 0.524 |
VS_2552 | mutM | VS_2552 | VS_0186 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoaE family. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.700 |
VS_2552 | nth | VS_2552 | VS_0971 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.452 |