node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_0604 | cobB | VS_0604 | VS_1480 | Inositol monophosphate family protein; Belongs to the inositol monophosphatase superfamily. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.683 |
VS_0604 | nadE | VS_0604 | VS_II0275 | Inositol monophosphate family protein; Belongs to the inositol monophosphatase superfamily. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.727 |
VS_0604 | nadK | VS_0604 | VS_0648 | Inositol monophosphate family protein; Belongs to the inositol monophosphatase superfamily. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.821 |
VS_1558 | VS_II0276 | VS_1558 | VS_II0276 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Hypothetical protein; Belongs to the NadD family. | 0.633 |
VS_1558 | VS_II0338 | VS_1558 | VS_II0338 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Amino acid permease. | 0.580 |
VS_1558 | VS_II0732 | VS_1558 | VS_II0732 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.539 |
VS_1558 | VS_II0733 | VS_1558 | VS_II0733 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.555 |
VS_1558 | cobB | VS_1558 | VS_1480 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.616 |
VS_1558 | nadE | VS_1558 | VS_II0275 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.646 |
VS_1558 | nadK | VS_1558 | VS_0648 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.704 |
VS_1558 | rsfS | VS_1558 | VS_0715 | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.563 |
VS_II0276 | VS_1558 | VS_II0276 | VS_1558 | Hypothetical protein; Belongs to the NadD family. | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.633 |
VS_II0276 | VS_II0338 | VS_II0276 | VS_II0338 | Hypothetical protein; Belongs to the NadD family. | Amino acid permease. | 0.682 |
VS_II0276 | VS_II0732 | VS_II0276 | VS_II0732 | Hypothetical protein; Belongs to the NadD family. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.708 |
VS_II0276 | VS_II0733 | VS_II0276 | VS_II0733 | Hypothetical protein; Belongs to the NadD family. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.677 |
VS_II0276 | cobB | VS_II0276 | VS_1480 | Hypothetical protein; Belongs to the NadD family. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.795 |
VS_II0276 | nadE | VS_II0276 | VS_II0275 | Hypothetical protein; Belongs to the NadD family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.951 |
VS_II0276 | nadK | VS_II0276 | VS_0648 | Hypothetical protein; Belongs to the NadD family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.806 |
VS_II0276 | rsfS | VS_II0276 | VS_0715 | Hypothetical protein; Belongs to the NadD family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.801 |
VS_II0338 | VS_1558 | VS_II0338 | VS_1558 | Amino acid permease. | Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.580 |