node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_1787 | VS_1788 | VS_1787 | VS_1788 | DnaK-related protein; Belongs to the heat shock protein 70 family. | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.621 |
VS_1787 | VS_1789 | VS_1787 | VS_1789 | DnaK-related protein; Belongs to the heat shock protein 70 family. | DnaK-related protein (fragment). | 0.950 |
VS_1787 | dnaJ | VS_1787 | VS_0652 | DnaK-related protein; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.943 |
VS_1787 | groL | VS_1787 | VS_0239 | DnaK-related protein; Belongs to the heat shock protein 70 family. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.844 |
VS_1787 | grpE | VS_1787 | VS_0649 | DnaK-related protein; Belongs to the heat shock protein 70 family. | Protein grpE (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.955 |
VS_1787 | htpG | VS_1787 | VS_2269 | DnaK-related protein; Belongs to the heat shock protein 70 family. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.981 |
VS_1787 | rplN | VS_1787 | VS_2821 | DnaK-related protein; Belongs to the heat shock protein 70 family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.530 |
VS_1787 | rpoH | VS_1787 | VS_3018 | DnaK-related protein; Belongs to the heat shock protein 70 family. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.561 |
VS_1788 | VS_1787 | VS_1788 | VS_1787 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DnaK-related protein; Belongs to the heat shock protein 70 family. | 0.621 |
VS_1788 | VS_1789 | VS_1788 | VS_1789 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DnaK-related protein (fragment). | 0.990 |
VS_1788 | dnaJ | VS_1788 | VS_0652 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.943 |
VS_1788 | groL | VS_1788 | VS_0239 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.844 |
VS_1788 | grpE | VS_1788 | VS_0649 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Protein grpE (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.955 |
VS_1788 | htpG | VS_1788 | VS_2269 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.981 |
VS_1788 | rplN | VS_1788 | VS_2821 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.530 |
VS_1788 | rpoH | VS_1788 | VS_3018 | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.561 |
VS_1789 | VS_1787 | VS_1789 | VS_1787 | DnaK-related protein (fragment). | DnaK-related protein; Belongs to the heat shock protein 70 family. | 0.950 |
VS_1789 | VS_1788 | VS_1789 | VS_1788 | DnaK-related protein (fragment). | Putative chaperone protein dnaK (Heat shock protein 70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.990 |
VS_1789 | dnaJ | VS_1789 | VS_0652 | DnaK-related protein (fragment). | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.943 |
VS_1789 | groL | VS_1789 | VS_0239 | DnaK-related protein (fragment). | 60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.844 |