node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_0323 | VS_1653 | VS_0323 | VS_1653 | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.742 |
VS_0323 | VS_2153 | VS_0323 | VS_2153 | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.742 |
VS_0323 | polA | VS_0323 | VS_0108 | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.651 |
VS_0323 | rnhA | VS_0323 | VS_2325 | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.744 |
VS_0323 | topA | VS_0323 | VS_1081 | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.974 |
VS_1653 | VS_0323 | VS_1653 | VS_0323 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.742 |
VS_1653 | VS_2153 | VS_1653 | VS_2153 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.613 |
VS_1653 | polA | VS_1653 | VS_0108 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.884 |
VS_1653 | rnhA | VS_1653 | VS_2325 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.740 |
VS_1653 | rnhB | VS_1653 | VS_2338 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.694 |
VS_1653 | topA | VS_1653 | VS_1081 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.667 |
VS_1653 | xni | VS_1653 | VS_2394 | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Probable exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.434 |
VS_1699 | rnhA | VS_1699 | VS_2325 | Fructose-2,6-bisphosphatase. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.672 |
VS_2153 | VS_0323 | VS_2153 | VS_0323 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.742 |
VS_2153 | VS_1653 | VS_2153 | VS_1653 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Putative Ribonuclease HI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.613 |
VS_2153 | polA | VS_2153 | VS_0108 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.884 |
VS_2153 | rnhA | VS_2153 | VS_2325 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.747 |
VS_2153 | rnhB | VS_2153 | VS_2338 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.782 |
VS_2153 | topA | VS_2153 | VS_1081 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.704 |
VS_2153 | xni | VS_2153 | VS_2394 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Probable exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.434 |