node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_1436 | VS_3095 | VS_1436 | VS_3095 | Hypothetical protein; Doubtful CDS. | ThiS. | 0.789 |
VS_1436 | VS_II1086 | VS_1436 | VS_II1086 | Hypothetical protein; Doubtful CDS. | Putative transcriptional activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.667 |
VS_1436 | VS_II1090 | VS_1436 | VS_II1090 | Hypothetical protein; Doubtful CDS. | Phosphomethylpyrimidine kinase. | 0.818 |
VS_1436 | thiC | VS_1436 | VS_3098 | Hypothetical protein; Doubtful CDS. | ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.828 |
VS_1436 | thiG | VS_1436 | VS_3094 | Hypothetical protein; Doubtful CDS. | ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.835 |
VS_1436 | thiM | VS_1436 | VS_II1085 | Hypothetical protein; Doubtful CDS. | Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.829 |
VS_1876 | VS_3095 | VS_1876 | VS_3095 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | ThiS. | 0.789 |
VS_1876 | VS_II1086 | VS_1876 | VS_II1086 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative transcriptional activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.668 |
VS_1876 | VS_II1090 | VS_1876 | VS_II1090 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Phosphomethylpyrimidine kinase. | 0.935 |
VS_1876 | thiC | VS_1876 | VS_3098 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.884 |
VS_1876 | thiG | VS_1876 | VS_3094 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.839 |
VS_1876 | thiM | VS_1876 | VS_II1085 | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.926 |
VS_3095 | VS_1436 | VS_3095 | VS_1436 | ThiS. | Hypothetical protein; Doubtful CDS. | 0.789 |
VS_3095 | VS_1876 | VS_3095 | VS_1876 | ThiS. | Putative MutT/nudix hydrolase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.789 |
VS_3095 | VS_3097 | VS_3095 | VS_3097 | ThiS. | ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.960 |
VS_3095 | VS_II1086 | VS_3095 | VS_II1086 | ThiS. | Putative transcriptional activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.704 |
VS_3095 | VS_II1090 | VS_3095 | VS_II1090 | ThiS. | Phosphomethylpyrimidine kinase. | 0.957 |
VS_3095 | thiC | VS_3095 | VS_3098 | ThiS. | ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.971 |
VS_3095 | thiE | VS_3095 | VS_II1083 | ThiS. | Putative thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.791 |
VS_3095 | thiG | VS_3095 | VS_3094 | ThiS. | ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |