STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHI_087430SWIRM domain-containing protein. (238 aa)    
Predicted Functional Partners:
25.t00034
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.999
14.t00031
Uncharacterized protein.
   
 0.999
130.t00015
Bromodomain protein, putative.
   
 
 0.999
158.t00013
40S ribosomal protein S27a, putative.
   
 0.999
275.t00007
Uncharacterized protein.
   
 0.999
60.t00011
Acetyltransferase, GNAT family.
   
 0.999
326.t00007
Proteasome regulatory subunit, putative.
   
 0.981
31.t00030
Proteasome subunit alpha type.
   
 0.980
167.t00006
Proteasome regulatory subunit, putative.
   
 0.979
4.t00010
26S protease regulatory subunit, putative; Belongs to the AAA ATPase family.
  
 0.972
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.