297.t00006 protein (Entamoeba histolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

297.t00006

5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (779 aa)

Predicted Functional Partners:

1.t00079

0.639

299.t00008

0.628

39.t00016

0.623

528.t00002

0.592

54.t00029

0.590

414.t00003

0.590

1.t00050

0.586

131.t00001

0.583

108.t00010

0.578

517.t00001

0.575

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00050	1.t00079	C4M1W2	C4LT45	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.756
1.t00050	131.t00001	C4M1W2	C4M010	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase, putative.	0.822
1.t00050	297.t00006	C4M1W2	C4M8Q3	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.586
1.t00050	299.t00008	C4M1W2	C4M9R3	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	Ribosome biogenesis protein BMS1, putative.	0.707
1.t00050	39.t00016	C4M1W2	C4LWT5	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	BP28CT domain-containing protein.	0.850
1.t00050	414.t00003	C4M1W2	C4M620	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase, putative.	0.496
1.t00050	517.t00001	C4M1W2	C4MAZ1	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	0.684
1.t00050	528.t00002	C4M1W2	C4MAW3	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	SnoRNA binding protein, putative.	0.764
1.t00079	1.t00050	C4LT45	C4M1W2	Uncharacterized protein.	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	0.756
1.t00079	131.t00001	C4LT45	C4M010	Uncharacterized protein.	DEAD/DEAH box helicase, putative.	0.950
1.t00079	297.t00006	C4LT45	C4M8Q3	Uncharacterized protein.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.639
1.t00079	299.t00008	C4LT45	C4M9R3	Uncharacterized protein.	Ribosome biogenesis protein BMS1, putative.	0.999
1.t00079	39.t00016	C4LT45	C4LWT5	Uncharacterized protein.	BP28CT domain-containing protein.	0.999
1.t00079	414.t00003	C4LT45	C4M620	Uncharacterized protein.	DEAD/DEAH box helicase, putative.	0.801
1.t00079	517.t00001	C4LT45	C4MAZ1	Uncharacterized protein.	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	0.856
1.t00079	528.t00002	C4LT45	C4MAW3	Uncharacterized protein.	SnoRNA binding protein, putative.	0.999
1.t00079	54.t00029	C4LT45	C4M5I5	Uncharacterized protein.	DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family.	0.767
108.t00010	131.t00001	C4M4B3	C4M010	Uncharacterized protein.	DEAD/DEAH box helicase, putative.	0.811
108.t00010	297.t00006	C4M4B3	C4M8Q3	Uncharacterized protein.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.578
108.t00010	414.t00003	C4M4B3	C4M620	Uncharacterized protein.	DEAD/DEAH box helicase, putative.	0.943