STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G6PIGlucose-6-phosphate isomerase; Belongs to the GPI family. (546 aa)    
Predicted Functional Partners:
PGM
Phosphoglucomutase, putative; Belongs to the phosphohexose mutase family.
  
 0.997
223.t00001
Fructose-1,6-bisphosphate aldolase, putative.
  
 
 0.996
HXK2
Phosphotransferase.
 
 
 
 0.994
HXK1
Phosphotransferase.
 
 
 
 0.993
202.t00008
Triosephosphate isomerase.
  
 0.991
345.t00008
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.990
337.t00001
Enolase, putative.
  
 0.990
248.t00008
Glucosamine--fructose-6-phosphate aminotransferase, putative.
  
 
 0.988
224.t00017
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.987
91.t00031
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK [...]
  
 0.987
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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