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EHI_176140 protein (Entamoeba histolytica) - STRING interaction network
"EHI_176140" - Profilin in Entamoeba histolytica
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
EHI_176140Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (130 aa)    
Predicted Functional Partners:
EHI_197550
Formin homology 2 family protein; Diaphanous protein, homolog 2, putative (986 aa)
     
 
  0.971
EHI_126070
Formin homology 2 family protein; Diaphanous protein, homolog 2, putative (769 aa)
       
 
  0.938
EHI_197480
Actophorin, putative ; Belongs to the actin-binding proteins ADF family (138 aa)
     
 
  0.880
EHI_122800
Coronin; Actin-binding protein, putative ; Belongs to the WD repeat coronin family (1602 aa)
     
 
  0.880
EHI_111050
Actin-like protein, putative ; Belongs to the actin family (401 aa)
     
 
  0.863
EHI_198930
Actin-related protein 3, putative ; Belongs to the actin family (416 aa)
     
 
  0.863
EHI_186770
Actin-binding protein, cofilin/tropomyosin family (343 aa)
       
 
  0.851
EHI_188820
Uncharacterized protein (540 aa)
       
 
  0.850
EHI_008780
Actin, putative ; Belongs to the actin family (763 aa)
     
 
  0.779
EHI_131230
Actin, putative ; Belongs to the actin family (876 aa)
     
 
  0.779
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica, Entamoeba histolytica
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