STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2UXN6_NAEGRPredicted protein. (452 aa)    
Predicted Functional Partners:
D2VJC0_NAEGR
Predicted protein.
   
 0.999
D2V820_NAEGR
Predicted protein.
    
 0.993
D2UYD3_NAEGR
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 0.981
D2VV01_NAEGR
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.958
D2VQ68_NAEGR
Transcription elongation factor SPT5.
   
 0.957
D2VNX5_NAEGR
Transcription elongation complex subunit.
   
 0.950
D2VP11_NAEGR
Predicted protein.
    
 0.943
D2VZ29_NAEGR
Predicted protein.
   
 0.924
D2W3Y1_NAEGR
Predicted protein.
    
 0.917
D2V7C0_NAEGR
Predicted protein.
   
 0.885
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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