STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2UZZ4_NAEGRPredicted protein. (189 aa)    
Predicted Functional Partners:
D2VSJ4_NAEGR
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.988
D2VPH4_NAEGR
Predicted protein.
  
 0.987
D2UZK9_NAEGR
Predicted protein.
  
 
 0.985
NAEGRDRAFT_473
Predicted protein.
  
 0.984
D2V2R7_NAEGR
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
 
 
 0.981
D2V2T6_NAEGR
Guanylate kinase.
  
 
 0.978
D2VDZ4_NAEGR
Predicted protein.
  
 
 0.978
D2UYP5_NAEGR
Predicted protein.
  
 0.976
D2VIC2_NAEGR
ADK_lid domain-containing protein; Belongs to the adenylate kinase family.
  
 
 0.955
D2VJP7_NAEGR
Adenylate kinase domain-containing protein; Belongs to the adenylate kinase family.
  
 
 0.955
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.