STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2V5S8_NAEGRSuccinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (515 aa)    
Predicted Functional Partners:
D2UZI7_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.981
D2V786_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.981
D2VQL9_NAEGR
Predicted protein.
  
 
 0.972
D2V7B8_NAEGR
Uncharacterized protein.
  
 
 0.971
D2VV98_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.961
D2UYB3_NAEGR
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    
 0.955
D2W0L2_NAEGR
Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.815
D2VGY2_NAEGR
Predicted protein.
    
 0.803
D2VSJ4_NAEGR
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.793
D2V5V4_NAEGR
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
      
 0.731
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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